$17.4M Saved Through Analytics-Driven Patient Blood Management Improvements

UnityPoint Health创建了一个工作队来制定和实施一项最大限度地管理血液的计划。工作队纳入了决策支持，以符合输血标准改进输血顺序。还利用了一个分析平台，监测世界杯厄瓜多尔vs塞内加尔波胆预测血液制品的使用情况，包括针对患者病例组合进行风险调整的预测模型，以及下至订购供应商级别的数据。

RED BLOOD CELL TRANSFUSION IN THE U.S.

在全国范围内，每年有1400万单位的红细胞输注。每次输血平均使用三个单位，每单位的成本为300美元。^1,2RBC transfusion can be life-saving, although sometimes it can also cause harm. This treatment is strongly associated with prolonged hospital stays as well as increased costs, morbidity, and early and late mortality.³

UnityPoint Health致力于在爱荷华州、伊利诺斯州西部和威斯康辛州南部提供卓越的医疗服务。其网络包括医院、诊所和家庭护理服务，每年有超过620万的患者访问，使用创新的先进技术为患者和家庭提供全方位的护理，为每一位患者每次提供最佳的结果。

RBC TRANSFUSION IMPROVEMENTS HINDERED BY DATA SHORTAGE

UnityPoint Health recognized that more than 10 percent of its inpatients received transfusions annually, costing the organization more than $12 million each year. One critical initiative identified to improve the quality of care and safety of RBC transfusion, and reduce cost, was blood management. These improvement efforts were hindered, however, by a lack of specific, actionable data, to generate insight into blood management improvement opportunities.

The organization needed a comprehensive, data-driven approach to improve the effectiveness of blood management. It also worked toward decreasing unwarranted variation to improve patient safety, conserve a valuable, limited resource, and drive down costs.

ANALYTICS DRIVE BLOOD MANAGEMENT PROCESS IMPROVEMENTS

To improve blood management, UnityPoint Health created a task force, directing the team to develop and implement a plan to maximize blood management. The task force was instructed to establish a culture promoting best blood management practices and non-punitive process improvement.

UnityPoint Health focused its improvement efforts on engaging providers in transitioning to the American Association of Blood Bank (AABB) transfusion standards, and implementing decision support to improve transfusion ordering in alignment with the transfusion standards. The organization implemented:

• 以血红蛋白(Hgb)水平作为住院病人输血的限制性策略。
• Promoted processes to ensure a preoperative anemia assessment and treatment before elective surgery.
• Procedures for improved surgical hemostasis, intraoperative bleeding management, and perioperative blood salvage – recovering the patient’s own blood, which is then filtered, washed, and returned to the patient.
• RBC订购决策支持——当供应商输入RBC输血订单时，需要对每个单位的RBC和输血单位之间的Hgb进行评估，决策支持工具将检查过去24小时内最近的Hgb。
  • The provider is informed if there is no Hgb, then prompted to order and review the Hgb before ordering a transfusion.
  • If Hgb is less than 7g/dL, there is no alert.
  • If the Hgb is greater than 7-8g/dL, the alert encourages the provider to reconsider transfusion, indicating transfusion is not recommended in hemodynamically stable patients.
  • 如果Hgb是8.1-9g/dL，警报概述了适合输血的情况。
  • 如果需要紧急/大量输血，可以绕过警报。

UnityPoint Health provided its interdisciplinary team education, increasing awareness of the risks of blood transfusions, the changes in related guidelines compared to what many were taught during medical or nursing school, and the improved patient outcomes associated with the AABB guidelines. The organization also leverages the Health Catalyst^®Data Operating System (DOS™) and a robust suite of analytics applications for its data and analytics needs, and uses the Blood Utilization Analytics Accelerator to monitor the utilization of blood products, including data down to the ordering provider level (see Figure 1).

The analytics accelerator is designed to monitor the effectiveness of UnityPoint Health’s blood management initiatives, and uses both historical descriptive statistics, and predictive modeling to risk-adjust blood utilization specific to patient case-mix.

The risk-adjustment model includes consideration of:

• First and lowest Hgbs on record.
• Hgb at the time of transfusion order.
• Diagnosis-related group for the patient’s illness.
• Severity of patient’s illness.
• 病人的年龄。
• 病人性别。

Using the risk-adjusted data in the analytics accelerator, UnityPoint Health is able to visualize utilization of RBCs, and is able to attribute variation in RBC transfusion to patient factors that necessitate higher utilization, or to variation in provider practice. The organization is then able to control for deviation in patient factors and isolate variation in provider practice to identify potential over-utilization of RBCs. Transfusion scenarios that may not have been appropriate can easily be identified and visualized. It can visualize patients who were transfused at Hgb levels far above the current guidelines, and also identify patients who were transfused at minimum Hgb closer to guidelines, but with a last Hgb that was much higher than transfusion thresholds (see Figure 2).

UnityPoint Health leaders can use the analytics accelerator to review individual patient cases that were transfused with RBCs without logging into the EMR. The data can be filtered by ordering provider, so all patients that contributed to a particular actual/ expected ratio can be viewed in one location.

The analytics accelerator data are updated monthly and available for hospital transfusion reviewers and providers giving them the ability to compare their transfusion performance with their peers. Leaders engage with providers to understand cases of overuse, identifying if the use was appropriate, and if not, working with the provider to change practices and adhere to the transfusion guidelines and most recent best practices, safeguarding the best possible patient outcome.

RESULTS

UnityPoint Health’s data-driven patient blood management improvements have helped improve patient safety by decreasing unnecessary RBC transfusion, ensuring patients receive care aligned with the most recent evidence. These efforts have also positively impacted financial performance across the system, including:

• $17.4M reduction in direct costs over six years, a result of decreasing unnecessary RBC transfusion.
• 58,089 fewer units of RBC transfused over six years.
• 15,601 patients avoided exposure to red blood cells by transfusion.

“The success of the UnityPoint Health blood management program reflects our commitment to continually improving patient safety while ensuring the best outcome for every patient.”

– Michael Kafka, MD, FACP Medical Director, Quality and Patient Safety

WHAT’S NEXT

UnityPoint Health plans to expand its use of predictive analytics to continue improving the care it provides patients.

参考文献

1. Society for the Advancement of Blood Management. (2018).Transfusion overuse – Exposing an international problem and patient safety issue.
2. American Red Cross. (2019).Blood needs & blood supply.
3. Murphy, G. J., Reeves, B. C., Rogers, C. A., Rizva, S. I. A., Culliford, L., & Angelini, G. D. (2007).Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery.Circulation, 116(22), 2544–2552.